The first legs will be on Tuesday 24 and Wednesday 25 April, with the returns on May 1 and 2.
Five-time European champions Liverpool are in the quarter-finals of this year's competition
Match-by-match facts and statistics ahead of the Premier League
Alexis Sanchez shrugged off an ankle injury and continued his resurgent form at the Copa America. The Chile striker fired his side to a 2-1 victory over Ecuador on Friday which took the holders into the quarter-finals of the competition.
Images from the English Premier League matches played on Saturday
The Merseysiders fell behind to a Raul Jimenez goal on the break in the 38th minute, the Mexican firing home confidently after Diogo Jota robbed James Milner.
Images from Sunday's English Premier League matches.
Manchester City were confirmed as English Premier League champions for the fifth time in six seasons on Saturday without even having to kick a ball.
Juergen Klopp's side returned to English Premier League action on Friday with a hunger and desire that suggested they have spent the close-season break chomping at the bit to get back on the field.
Manchester City suffered their first home Premier League loss in eight months as a shock 3-2 defeat by Crystal Palace on Saturday left Pep Guardiola's champions trailing leaders Liverpool by four points.
Real Madrid produced a stunning comeback from two goals down to earn a devastating 5-2 victory at Liverpool
A summary of Saturday's matches in the English Premier League.
Images from Saturday's action in the English Premier League.
Chelsea ripped apart Premier League title rivals Arsenal in a 6-0 mauling at Stamford Bridge on Saturday to ensure Arsene Wenger's 1,000th game turned sour and Liverpool and Manchester City kept up the pressure with big wins.
A summary of Friday's action in the Premier League.
European champions Liverpool made an emphatic start to the new Premier League season by scoring three times in the opening half an hour as they taught promoted Norwich City a harsh lesson with a 4-1 thrashing at Anfield on Friday.
Liverpool will be given a guard of honour by City's players when the top two sides meet at the Etihad on Thursday.
With 27 wins and 82 points under their belt after only one defeat all season, red-hot Liverpool set a record-breaking pace to leave teams behind them in their wake and are six points shy of ending a 30-year wait for the top-flight title.
Jurgen Klopp has agreed a contract extension with Liverpool until 2024
Two goals each for Roberto Firmino and Sadio Mane helped Liverpool to keep in touch with Premier League leaders Manchester City with a 4-2 win over lowly Burnley at Anfield on Sunday.
Barcelona were held to a frustrating 0-0 draw at Olympique Lyonnais in their Champions League last-16 first leg on Tuesday as both sides remained unbeaten in this season's competition.
Real Madrid coach Zinedine Zidane has warned Liverpool that his side are as hungry as ever to win the Champions League, rejecting claims that the Spanish giants might have lost their edge ahead of Saturday's final in Kiev.
Liverpool's livewire Sadio Mane scored one goal and played a crucial part in the other as they reclaimed the Premier League's top spot with a scrappy 2-1 win at second bottom Fulham on Sunday.
Images from the English Premier League matches played on Saturday night.
Images from the English Premier League matches played on Saturday
The win moved Liverpool level with City on 86 points in the standings
After an uncharacteristically slow start to the season which provoked questions about his longevity, Cristiano Ronaldo has roared back to life with a torrent of goals and now has La Liga's top scorer award in his sights.
Liverpool snatched three points with a wild 1-0 victory over relegation-threatened Nottingham Forest.
Juergen Klopp refused to dwell on the two late goals they conceded in a 5-2 win over AS Roma in their Champions League semi-final, first leg on Tuesday, saying his team had been 'perfect' for 80 minutes.
Messi ran amok at Wembley Stadium, slicing Spurs apart with incisive passes from deep, such as the one that allowed Philippe Coutinho to open the scoring, and was as dangerous as ever in front of goal, firing in the Catalan side's final two goals to end their winless run of three games.
Chelsea paid a heavy price for a 3-2 defeat at West Ham United as first Liverpool, then Manchester City, leapfrogged them in the English Premier League title race on Saturday, with City ending the day on top for the first time this season.
'It's a prize that's called The Best and the guy who is, for us, the best player in the world wasn't there.'
Manchester City took a slender lead from the first leg of their Champions League quarter-final after Kevin De Bruyne's 70th minute goal earned them a 1-0 win over Atletico Madrid at the Etihad Stadium on Tuesday. In anothr match, Liverpool took a firm grip of their Champions League tie with Benfica as goals from Ibrahima Konate, Sadio Mane and Luis Diaz earned them a 3-1 victory in Lisbon.
Napoli striker Gonzalo Higuain and evergreen AS Roma forward Francesco Totti lit up Serie A on Monday as the two teams won in contrasting fashion to boost their bids for an automatic Champions League spot.
The Russian Football Union's anti-discrimination inspector has said the World Cup is a chance for Russia to show how open it is.
Images from the English Premier League matches played on Wednesday
Russia is the lowest FIFA ranked side at the event, but two games in they are top of their group with six points and are poised to qualify for the next stage.
Muslim soccer fans visiting Russia for the World Cup celebrated the end of the fasting month of Ramadan on Friday, with Egyptian fans hoping the festival would bring their national team good luck in a match with Uruguay later in the day.
A round-up of Tuesday's action in the UEFA Champions League.
